The human gut houses one of the most diverse and rich ecosystem known to man. Inside each and every one of us is a community of over one trillion microbes from over 500 different species. These microbes and their associated genes are known collectively as the ‘microbiome’. Recent advances in sequencing technology have allowed the scientific and medical community to study the microbiome in a high-throughput and precise manner. These advances coupled with ground-breaking research has uncovered that the microbiome plays a pivotal role in many critical physiological and biological functions, ranging from vitamin production to the regulation of the immune system.
Two key concepts in the field of human gut microbiome science are diversity and structural/functional balance. Under normal circumstances, the microbial communities live in balance (symbiosis) with their human hosts. However, imbalances in structure and function (dysbiosis) can occur through external factors such as antibiotics or other factors such as a person’s diet or genetic makeup. Several studies have implicated reduced dysbiosis of gut microbiome with a wide variety of diseases, ranging from acute infections caused by the bacterium C.difficile, to complicated chronic conditions like obesity, liver disease and inflammatory bowel disease. Interestingly, the relationship between the bacteria the microbiome and health stretches further than the gut itself. There is even evidence that links dysbiosis to diseases of the brain and nervous system such as Parkinson’s and Multiple Sclerosis.
As imbalances within the microbiome are associated with a variety of diseases, addressing dysbiosis through medicinal products that restore symbiosis offers an exciting new treatment avenue for patients. Click here to learn more about how EnteroBiotix is pioneering this exciting field of science and medicine.